When doctors can't get through to Bender, they order a robotomy.
The world watches in terror as billions of tentacles emerge from the anomaly. Leela, Amy, and Zap become the only resistance.
Everybody in the Universe and Yivo live together happily, except for a skeptical Leela. Bender misses the humans.
When Leela loses her cool over some redneck bullies, Farnsworth orders her to wear an electrical collar to help control her temper; and Bender loses his mind over Dungeons and Dragons.
While Bender is getting a robotomy, Farnsworth, Leela, and Fry wind up with Bender in his imaginary world of Dungeons and Dragons.