As Leela and Lars prepare to get married, we learn what happened to Fry when he returned to the 21st century.
Alien scammers buy the planet and banish its inhabitants to Neptune, leading to an intergalactic battle for Earth.
The Planet Express crew mounts a mission to explore an anomalous rift in space; and Fry gets serious about his new girlfriend, Colleen.
Zap leads a military strike on the anomaly; a heartbroken Fry decides to leave the Universe.
The world watches in terror as billions of tentacles emerge from the anomaly. Leela, Amy, and Zap become the only resistance.