In Part One of a special two-part story, Brian meets and quickly falls in love with a woman named Jess, who reveals she has cancer. After she receives devastating news regarding her diagnosis, Brian proposes marriage to her.
In Part Two of a special two-part story, Brian's marriage to Jess is not what he envisioned, especially after her miraculous recovery from cancer.
To Stewie's surprise, he quickly befriends a boy his age, but is devastated when he realizes he isn't invited to his birthday party. Meanwhile, Peter and Lois attend a self-empowerment seminar.
After Brian teases Stewie for being small, Stewie invents a shrinking machine that results in both of them shrinking to a microscopic size.
Brian worries about the legacy he's leaving behind, so Stewie makes a robot duplicate as a living biography.
